Acquired nephrogenic diabetes insipidus happens when the small tubes or tubules in the kidneys are defective causing a person to eliminate too much water during urination.
This occurs because the kidneys do not respond to antidiuretic hormone (ADH)or vasopressin. ADH tells the kidneys to make the urine more concentrated.
Symptoms of acquired nephrogenic diabetes insipidus are extreme thirst especially for ice water and production of large amounts of urine.
This commonly occurs because of a problem caused by something else such as blockage in the urinary tract, use of certain medications, high levels of calcium, or low levels of potassium. This acquired nephrogenic diabetes insipidus is an extremely rare form of diabetes. When the cause of this form of diabetes inspidus is identified and corrected, the disease usually clears up.
Hereditary nephrogenic diabetes insipidus is treated with fluid intake that matches urine output and medication to lower urine output. Medications used to treat nephrogenic diabetes insipidus include anti-inflammatory medication indomethacin and diuretics such as amiloride and hydrochlorothiazide (HCTZ).
Another form of diabetes insipidus is known as control diabetes insipidus because the area that controls the retaining of fluid is where the problem lies. There can be several causes for this type of diabetes. It is usually caused by damage to the pituitary gland or hypothalamus because of infection, surgery, tumor, or head injury. It is these glands that control the amount of ADH that is sent to the kidneys.
Complications of diabetes insipidus, whether acquired nephrogenic diabetes insipidus or control diabetes insipidus, can be caused by dehydration which causes dry skin, fever, weight loss and rapid heart beat and electrolyte imbalance which causes fatigue, irritability, headache and muscle pains. If you develop any of the symptoms or complications that are related to diabetes insipidus, you should meet with your primary care physician as quickly as possible.
There is currently no way to prevent acquired nephrogenic diabetes insipidus but the prognosis when diagnosed is good when the underlying reason for this problem with the kidneys is identified and corrected.
Acquired nephrogenic diabetes insipidus occurs when the small tubes or tubules in the kidneys are defective causing a person to eliminate too much water during urination.
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